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Bioinformatics with Python Cookbook

You're reading from   Bioinformatics with Python Cookbook Learn how to use modern Python bioinformatics libraries and applications to do cutting-edge research in computational biology

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Product type Paperback
Published in Jun 2015
Publisher
ISBN-13 9781782175117
Length 306 pages
Edition 1st Edition
Languages
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Toc

Table of Contents (11) Chapters Close

Preface 1. Python and the Surrounding Software Ecology 2. Next-generation Sequencing FREE CHAPTER 3. Working with Genomes 4. Population Genetics 5. Population Genetics Simulation 6. Phylogenetics 7. Using the Protein Data Bank 8. Other Topics in Bioinformatics 9. Python for Big Genomics Datasets Index

Managing datasets with PLINK

Here, we will manage our dataset using PLINK. We will create subsets of our main dataset (from the HapMap project) suitable to be analyzed in our next recipes.

Tip

Note that neither PLINK nor any similar programs were developed because of their file formats. Probably, it had no objective to become a default file standard for population genetics data. In this field, you will need to be ready to convert from format to format (for this, Python is quite appropriate) because every application that you will use will probably have its own quirky requirements. The most important point to learn from this recipe is that it's not formats that are being used, although these are relevant, but the ''file conversion mentality''. Apart from this, some of the steps in this recipe also convey genuine analysis techniques that you may want to consider using (for example, subsampling or Linkage Disequilibrium (LD) pruning).

Getting ready

Throughout this chapter...

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