Programs in the Windows environment communicate with the system by using Windows APIs. These APIs are built around the file system, memory management (including processes, the stack, and allocations), the registry hive, network communication, and so forth. Regarding reverse engineering, a wide coverage of these APIs and their library modules is a good advantage when it comes to easily understanding how a program works when seen in its low-level language equivalent. So, the best way to begin exploring APIs and their libraries would be to develop some programs ourselves.
There are many high-level languages used by developers like C, C++, C#, and Visual Basic. C, C++, and Visual Basic (native) compile to an executable that directly executes instructions in the x86 language. C# and Visual Basic (p-code) are usually compiled to use interpreters as a layer that turns...