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Biostatistics with Python

You're reading from   Biostatistics with Python Apply Python for biostatistics with hands-on biomedical and biotechnology projects

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Product type Paperback
Published in Nov 2024
Publisher Packt
ISBN-13 9781837630967
Length 374 pages
Edition 1st Edition
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Author (1):
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Darko Medin Darko Medin
Author Profile Icon Darko Medin
Darko Medin
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Table of Contents (24) Chapters Close

Preface 1. Part 1:Introduction to Biostatistics and Getting Started with Python
2. Chapter 1: Introduction to Biostatistics FREE CHAPTER 3. Chapter 2: Getting Started with Python for Biostatistics 4. Chapter 3: Exercise 1 – Cleaning and Describing Data Using Python 5. Chapter 4: Part 1 Exemplar Project – Load, Clean, and Describe Diabetes Data in Python 6. Part 2:Introduction to Python for Biostatistics – Methodology and Examples
7. Chapter 5: Introduction to Python for Biostatistics 8. Chapter 6: Biostatistical Inference Using Hypothesis Tests and Effect Sizes 9. Chapter 7: Predictive Biostatistics Using Python 10. Chapter 8: Part 2 Exercise – T-Test, ANOVA, and Linear and Logistic Regression 11. Chapter 9: Biostatistical Inference and Predictive Analytics Using Cardiovascular Study Data 12. Part 3:Clinical Study Design, Analysis, and Synthesizing Evidence
13. Chapter 10: Clinical Study Design 14. Chapter 11: Survival Analysis in Biomedical Research 15. Chapter 12: Meta-Analysis – Synthesizing Evidence from Multiple Studies 16. Chapter 13: Survival Predictive Analysis and Meta-Analysis Practice 17. Chapter 14: Part 3 Exemplar Project – Meta-Analysis of Survival Data in Clinical Research 18. Part 4:Biological and Statistical Variables and Frameworks, and a Final Practical Project from the Field of Biology
19. Chapter 15: Understanding Biological Variables 20. Chapter 16: Data Analysis Frameworks and Performance for Life Sciences Research 21. Chapter 17: Part 4 Exercise – Performing Statistics for Biology Studies in Python 22. Index 23. Other Books You May Enjoy

Implementing Cox (proportional gazards) regression in Python

Now we will use another package to perform a specific method called Cox proportional hazards regression. First, let’s discuss the method itself.

Cox proportional hazard regression is a statistical method used in survival analysis to evaluate the relationship between the time until an event of interest occurs and predictor variables. This method was developed by Sir David Cox in 1972.

What is very good about this type of regression is that it can handle censoring of the data and allow us to create multivariate models. This is very useful when we want to add other covariates in the survival analysis, or adjust for other covariates such as age or type of tumors in oncology.

The Cox model is based on the hazard function, which describes the instantaneous rate of failure at a given time. The hazard is assumed to be proportional across different levels of the predictor variables. One of the key assumptions of the...

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